When you open the Source Control Explorer from the Team Explorer window and then open a solution, if the Solution Explorer window is docked with the Team Explorer window, as in the attached screenshot, there is no indication that the solution has loaded.

I have three monitors at work. I was looking forward to get multiple monitor support in VS2010, but I can't see how to do the on thing that I wanted to do which is to tab code windows on another monitor. It's possible to float a code window, but it's impossible to create a Vertical Tab Group and maximize it to a single screen, therefore it's hard to display several code windows on a single screen. I would highly suggest allowing tabbed code windows to be moved to a separate monitor.

Whenever a new VisualStudio comes out I try to use it without Resharper. But it's always/still missing so many things or they aren't as comfortable to use as in Resharper. I recommend you simply remove all duplicate functionality and let Resharper do them right.

Add Better Multiple Monitor Support.
While you can free-float containers in other monitors, I would like to see the ability to add "Child" Visual Studio MDI Containers to other monitors. This would allow a user to move controls from one Container to another, dock, expand, maximize, etc. This should also support multiple "Tabs" of code in each container as well.

There are so many options in the Tools|Options dialog that it's very easy to forget exactly where you found a given option earlier. It would be nice if we could search for options in the Options dialog, along the lines what the beta of VS2011 is supposed to have with searching for commands.

In previous versions of Visual Studio, when you added a macro to a toolbar (via customize) you could draw a new icon to represent that macro on the toolbar.
Please bring this functionality back.

Hide project references in add refence dialogue box that have already been added to a project (or grey them out to show they've already been added).

Make the window bar stand out a bit more (different color than the rest of the window)

The functionality of Visual Studio is not what is bothering me so much. It is how ridiculously huge the menus are becoming - mostly in regards to the context menus surrounding the Solution Explorer.

I realize a lot of users have finally become accustomed to the layout, but the sheer number of menu options is becoming burdensome, especially on smaller screens like Ultrabooks.

Enclosed is a screenshot just to demonstrate...

Better color printing support.

With Windows 8 you can specify a connection as metered. Would be great if VS would be aware of this and turn off things like update & extension checks.

Make the title bold or something, I'm dying here.

Include in a separate tab in the Add reference dialog the list of folders that have been recently browsed (also, remember tab selection and last selected folder)

When I use "Go to Definition" for something defined in a DLL, it takes me to metadata. I would like to be able to use "Find all References" from here so I can find where a specific method or property is used. This can be done from any use within the project, but not from metadata.

INSTEAD OF REMOVING THE PROJECTS , WHY NOT DISABLE THEM OR ONLY DISABLE PROJECTS THAT USER WANTS TO DISABLE MANUALLY.

C# , VB , C++, ETC PROJECTS SHOULD BE DISABLED|ENABLED BY THE USER INSTEAD OF REMOVING THEM COMPLETELY.